Definitions of c jun Proto Oncogene

  1. Retrovirus- associated DNA sequences ( jun) originally isolated from the avian sarcoma virus 17 ( ASV 17). The proto- oncogene jun ( c- jun) codes for a nuclear protein which is involved in growth- related transcriptional control. Insertion of c- jun into ASV- 17 or the constitutive expression of the c- jun protein produces tumorgenicity. The human c- jun gene is located at 1p31- 32 on the short arm of chromosome 1.