Definitions of c fos Proteins

  1. Cellular DNA- binding proteins encoded by the c- fos genes ( GENES, FOS). They are involved in growth- related transcriptional control. c- fos combines with c- jun ( PROTO- ONCOGENE PROTEINS C- JUN) to form a c- fos/ c- jun heterodimer ( TRANSCRIPTION FACTOR AP- 1) that binds to the TRE ( TPA- responsive element) in promoters of certain genes.