Definitions of c erbB 2 Genes

  1.   The erbB 2 gene is a proto oncogene that codes for the erbB 2 receptor RECEPTOR ERBB 2 a protein with structural features simular to the epidermal growth factor receptor Its name originates from the viral oncogene homolog v erbB which is a truncated form of the chicken erbB gene found in the avian erythoblastosis virus Overexpression and amplification of the gene is associated with a significant number of adenocarcinomas The human c erbB 2 gene is located at 17q21 2