C BCL 1 PROTO ONCOGENES
\sˈiː bˌiːsˌiːˈɛl wˈɒn pɹˈə͡ʊtə͡ʊ ˈɒnkə͡ʊd͡ʒˌiːnz], \sˈiː bˌiːsˌiːˈɛl wˈɒn pɹˈəʊtəʊ ˈɒnkəʊdʒˌiːnz], \s_ˈiː b_ˌiː_s_ˌiː__ˈɛ_l w_ˈɒ_n p_ɹ_ˈəʊ_t_əʊ ˈɒ_n_k_əʊ_dʒ_ˌiː_n_z]\
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The B-cell leukemia/lymphoma-1 genes, associated with various neoplasms when overexpressed. Overexpression results from the t (11;14) translocation, which is characteristic of mantle zone-derived B-cell lymphomas. The human c-bcl-1 gene is located at 11q13 on the long arm of chromosome 18.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.