BURDACH'S COLUMN

\bˈɜːdat͡ʃɪz kˈɒlʌm], \bˈɜːdat‍ʃɪz kˈɒlʌm], \b_ˈɜː_d_a_tʃ_ɪ_z k_ˈɒ_l_ʌ_m]\

Definitions of BURDACH'S COLUMN

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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