BUDGET DEFICIT
\bˈʌd͡ʒɪt dˈɛfɪsˌɪt], \bˈʌdʒɪt dˈɛfɪsˌɪt], \b_ˈʌ_dʒ_ɪ_t d_ˈɛ_f_ɪ_s_ˌɪ_t]\
Definitions of BUDGET DEFICIT
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ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.