BRCA1 GENE PRODUCT
\bˌiːˌɑːsˌiːˈe͡ɪ wˈɒn d͡ʒˈiːn pɹˈɒdʌkt], \bˌiːˌɑːsˌiːˈeɪ wˈɒn dʒˈiːn pɹˈɒdʌkt], \b_ˌiː__ˌɑː_s_ˌiː__ˈeɪ w_ˈɒ_n dʒ_ˈiː_n p_ɹ_ˈɒ_d_ʌ_k_t]\
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The phosphoprotein encoded by the BRCA1 gene (GENE, BRCA1). In normal cells the BRCA1 protein is localized in the nucleus, whereas in the majority of breast cancer cell lines and in malignant pleural effusions from breast cancer patients, it is localized mainly in the cytoplasm. (Science 1995;270 (5237):713,789-91)
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Nearby Words
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