\bˈə͡ʊənz dɪzˈiːz], \bˈəʊənz dɪzˈiːz], \b_ˈəʊ_ə_n_z d_ɪ_z_ˈiː_z]\
Definitions of BOWENS DISEASE
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A persistent progressive non-elevated red scaly or crusted plaque which is due to an intradermal carcinoma and is potentially malignant. Atypical squamous cells proliferate through the whole thickness of the epidermis. The lesions may occur anywhere on the skin surface or on mucosal surfaces. The cause most frequently found is trivalent arsenic compounds. Freezing, cauterization or diathermy coagulation is often effective. (From Rook et al., Textbook of Dermatology, 4th ed, pp2428-9)
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HLA A2 Antigen
- Human histocompatibility (HLA) surface encoded by locus on chromosome 6. The HLA-A2 antigen is associated with recognition of INFLUENZA A VIRUS.