BIOLOGICAL ASSAY
\bˌa͡ɪəlˈɒd͡ʒɪkə͡l ɐsˈe͡ɪ], \bˌaɪəlˈɒdʒɪkəl ɐsˈeɪ], \b_ˌaɪ_ə_l_ˈɒ_dʒ_ɪ_k_əl ɐ_s_ˈeɪ]\
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A method of measuring the effects of a biologically active substance using an intermediate in vivo or in vitro tissue or cell model under controlled conditions. It includes virulence studies in animal fetuses in utero, mouse convulsion bioassay of insulin, quantitation of tumor-initiator systems in mouse skin, calculation of potentiating effects of a hormonal factor in an isolated strip of contracting stomach muscle, etc.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.