BENNET'S CORPUSCLES

\bˈɛnɪts kˈɔːpʌskə͡lz], \bˈɛnɪts kˈɔːpʌskə‍lz], \b_ˈɛ_n_ɪ_t_s k_ˈɔː_p_ʌ_s_k_əl_z]\

Definitions of BENNET'S CORPUSCLES

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1920 - A practical medical dictionary.
By Stedman, Thomas Lathrop

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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