BAYR5417
\bˈe͡ɪ ˈɑː fˈa͡ɪv θˈa͡ʊzənd fˈɔːhˈʌndɹədən sˈɛvəntˌiːn], \bˈeɪ ˈɑː fˈaɪv θˈaʊzənd fˈɔːhˈʌndɹədən sˈɛvəntˌiːn], \b_ˈeɪ ˈɑː f_ˈaɪ_v θ_ˈaʊ_z_ə_n_d f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d_ə_n s_ˈɛ_v_ə_n_t_ˌiː_n]\
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A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.