BASILAR ARTERY ANEURYSM
\bˈazɪləɹ ˈɑːtəɹi ˈanjuːɹˌɪzəm], \bˈazɪləɹ ˈɑːtəɹi ˈanjuːɹˌɪzəm], \b_ˈa_z_ɪ_l_ə_ɹ ˈɑː_t_ə_ɹ_i_ ˈa_n_j_uː_ɹ_ˌɪ_z_ə_m]\
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Congenital or acquired abnormal outpouching of an intracranial blood vessel wall. Saccular (berry) aneurysms are the most common variant, and tend to form at arterial branch points near the base of the brain. Rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (>2.5 cm in diameter) may compress adjacent structures, including the OCULOMOTOR NERVE (see also OCULOMOTOR NERVE DISEASES). (From Adams et al., Principles of Neurology, 6th ed, p841)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.