B CELL ACTIVATION ANTIGEN
\bˈiː sˈɛl ˌaktɪvˈe͡ɪʃən ˈantɪd͡ʒˌɛn], \bˈiː sˈɛl ˌaktɪvˈeɪʃən ˈantɪdʒˌɛn], \b_ˈiː s_ˈɛ_l ˌa_k_t_ɪ_v_ˈeɪ_ʃ_ə_n ˈa_n_t_ɪ_dʒ_ˌɛ_n]\
Definitions of B CELL ACTIVATION ANTIGEN
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The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production.
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