B 518
\bˈiː fˈa͡ɪvhˈʌndɹədən ˈe͡ɪtiːn], \bˈiː fˈaɪvhˈʌndɹədən ˈeɪtiːn], \b_ˈiː f_ˈaɪ_v_h_ˈʌ_n_d_ɹ_ə_d_ə_n ˈeɪ_t_iː_n]\
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Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active ALDOPHOSPHAMIDE. It is used in the treatment of lymphomas, leukemias, etc. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.