AUTONOMIC DYSREFLEXIAS
\ɔːtənˈɒmɪk dˌɪsɹɪflˈɛksi͡əz], \ɔːtənˈɒmɪk dˌɪsɹɪflˈɛksiəz], \ɔː_t_ə_n_ˈɒ_m_ɪ_k d_ˌɪ_s_ɹ_ɪ_f_l_ˈɛ_k_s_iə_z]\
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A syndrome associated with damage to the spinal cord above the mid thoracic level (see SPINAL CORD INJURIES) characterized by a marked increase in the sympathetic response to minor stimuli such as bladder or rectal distention. Manifestations include HYPERTENSION; TACHYCARDIA (or reflex bradycardia); FEVER; FLUSHING; and HYPERHIDROSIS. Extreme hypertension may be associated with a CEREBROVASCULAR ACCIDENT. (From Adams et al., Principles of Neurology, 6th ed, pp538 and 1232; J Spinal Cord Med 1997;20 (3):355-60)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.