ASTHMA THYMICUM
\ˈasmə θˈa͡ɪmɪkəm], \ˈasmə θˈaɪmɪkəm], \ˈa_s_m_ə θ_ˈaɪ_m_ɪ_k_ə_m]\
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A disease of infants, characterized by suspension of respiration at intervals; great difficulty of breathing, especially on waking, swallowing, or crying; ending often in a fit of suffocation, with convulsions. The pathology of the disease has been supposed to consist in an enlargement of the thymus gland, or of the glands of the neck pressing on the pneumo-gastric nerves[?]. The ear, by auscultation, at a distance from the chest, detects an incomplete, acute, hissing inspiration, or rather cry; whilst the expiration and voice are croupal, both at the accession and termination of the paroxysm. The heart's action has been observed to be distinct and feeble. These symptoms are often accompanied by rigidity of the fingers and toes; the thumb being frequently drawn forcibly into the palm of the clenched hand, whence the name Carpo-pedal spasm, applied, at times, to the disease.
By Robley Dunglison
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.