ASSECTATION

\ɐsɪktˈe͡ɪʃən], \ɐsɪktˈe‍ɪʃən], \ɐ_s_ɪ_k_t_ˈeɪ_ʃ_ə_n]\
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1790 - A Complete Dictionary of the English Language
By Thomas Sheridan

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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