APPEARANCE DAY

\ɐpˈi͡əɹəns dˈe͡ɪ], \ɐpˈi‍əɹəns dˈe‍ɪ], \ɐ_p_ˈiə_ɹ_ə_n_s d_ˈeɪ]\
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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black
 
1856 - A Law Dictionary
By John Bouvier

Word of the day

ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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