APPEARANCE BY ATTORNEY

\ɐpˈi͡əɹəns ba͡ɪ ɐtˈɜːni], \ɐpˈi‍əɹəns ba‍ɪ ɐtˈɜːni], \ɐ_p_ˈiə_ɹ_ə_n_s b_aɪ ɐ_t_ˈɜː_n_i]\

Definitions of APPEARANCE BY ATTORNEY

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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