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A family of Primates consisting of three genera: Pongo (PONGO PYGMAEUS), Pan (PAN TROGLODYTES and PAN PANISCUS), and Gorilla (GORILLA GORILLA). They inhabit forests in southeast Asia, equatorial Africa, Sumatra, and Borneo. The members of this family are the closest living relatives of man.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.