ANTIBIOTIC A23187
\ˌantɪba͡ɪˈɒtɪk ˌe͡ɪ twˈɛntiθɹˈiː θˈa͡ʊzənd wˈɒnhˈʌndɹədən ˈe͡ɪtisˈɛvən], \ˌantɪbaɪˈɒtɪk ˌeɪ twˈɛntiθɹˈiː θˈaʊzənd wˈɒnhˈʌndɹədən ˈeɪtisˈɛvən], \ˌa_n_t_ɪ_b_aɪ_ˈɒ_t_ɪ_k ˌeɪ t_w_ˈɛ_n_t_i_θ_ɹ_ˈiː θ_ˈaʊ_z_ə_n_d_ w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n ˈeɪ_t_i_s_ˈɛ_v_ə_n]\
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An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems.
By DataStellar Co., Ltd
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