ANIMALS INBRED STRAINS
\ˈanɪmə͡lz ˈɪnbɹɛd stɹˈe͡ɪnz], \ˈanɪməlz ˈɪnbɹɛd stɹˈeɪnz], \ˈa_n_ɪ_m_əl_z ˈɪ_n_b_ɹ_ɛ_d s_t_ɹ_ˈeɪ_n_z]\
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Animals produced by the mating of littermates or siblings over multiple generations. The resultant strain of animals is virtually identical genotypically. Highly inbred animal lines allow the study of certain traits in a relatively pure form. (Segen, Dictionary of Modern Medicine, 1992)
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Word of the day
Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.