ALPHA 1 ANTIPROTEINASE
\ˈalfə wˈɒn ˌantɪpɹˈə͡ʊtɪnˌe͡ɪs], \ˈalfə wˈɒn ˌantɪpɹˈəʊtɪnˌeɪs], \ˈa_l_f_ə w_ˈɒ_n ˌa_n_t_ɪ_p_ɹ_ˈəʊ_t_ɪ_n_ˌeɪ_s]\
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Plasma glycoprotein member of the serpin superfamily which inhibits trypsin, neutrophil elastase, and other proteolytic enzymes. Commonly referred to as alpha 1-proteinase inhibitor (A1PI), it exists in over 30 different biochemical variant forms known collectively as the Pi (protease inhibitor) system. Hereditary A1PI deficiency is associated with pulmonary emphysema.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.