ALBERT-CHAIN

\ˈalbətt͡ʃˈe͡ɪn], \ˈalbətt‍ʃˈe‍ɪn], \ˈa_l_b_ə_t_tʃ_ˈeɪ_n]\

Definitions of ALBERT-CHAIN

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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