ADRIABLASTIN
\ˈadɹɪəblˌastɪn], \ˈadɹɪəblˌastɪn], \ˈa_d_ɹ_ɪ__ə_b_l_ˌa_s_t_ɪ_n]\
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Antineoplastic antibiotic obtained from Streptomyces peucetics. It is a hydroxy derivative of DAUNORUBICIN and is used in treatment of both leukemia and solid tumors.
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.