ACTIVATED PROTEIN C RESISTANCE
\ˈaktɪvˌe͡ɪtɪd pɹˈə͡ʊtiːn sˈiː ɹɪsˈɪstəns], \ˈaktɪvˌeɪtɪd pɹˈəʊtiːn sˈiː ɹɪsˈɪstəns], \ˈa_k_t_ɪ_v_ˌeɪ_t_ɪ_d p_ɹ_ˈəʊ_t_iː_n s_ˈiː ɹ_ɪ_s_ˈɪ_s_t_ə_n_s]\
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A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.