ACQUIRED NEUROMYOTONIA
\ɐkwˈa͡ɪ͡əd njˌuːɹəmɪətˈə͡ʊni͡ə], \ɐkwˈaɪəd njˌuːɹəmɪətˈəʊniə], \ɐ_k_w_ˈaɪə_d n_j_ˌuː_ɹ_ə_m_ɪ__ə_t_ˈəʊ_n_iə]\
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A rare neuromuscular disorder with onset usually in late childhood or early adulthood, characterized by intermittent or continuous widespread involuntary muscle contractions; FASCICULATION; hyporeflexia; MUSCLE CRAMP; MUSCLE WEAKNESS; HYPERHIDROSIS; TACHYCARDIA; and MYOKYMIA. Involvement of pharyngeal or laryngeal muscles may interfere with speech and breathing. The continuous motor activity persists during sleep and general anesthesia (distinguishing this condition from STIFF-PERSON SYNDROME). Familial and acquired (primarily autoimmune) forms have been reported. (From Ann NY Acad Sci 1998 May 13;841:482-496; Adams et al., Principles of Neurology, 6th ed, p1491)
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Word of the day
hydromorphic
- [Greek] Structurally adapted to an aquatic environment, as organs of water plants.