ACETYLAMINOFLUORENE
\ˈasɪtˌɪlɐmˌɪnəflˌʊ͡əɹiːn], \ˈasɪtˌɪlɐmˌɪnəflˌʊəɹiːn], \ˈa_s_ɪ_t_ˌɪ_l_ɐ_m_ˌɪ_n_ə_f_l_ˌʊə_ɹ_iː_n]\
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A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the arylhydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
By DataStellar Co., Ltd
Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.