ABNORMAL RETURN

\ɐbnˈɔːmə͡l ɹɪtˈɜːn], \ɐbnˈɔːmə‍l ɹɪtˈɜːn], \ɐ_b_n_ˈɔː_m_əl ɹ_ɪ_t_ˈɜː_n]\

Definitions of ABNORMAL RETURN

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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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