ABDUCENS NERVE DISEASE

\ɐbdjˈuːsənz nˈɜːv dɪzˈiːz], \ɐbdjˈuːsənz nˈɜːv dɪzˈiːz], \ɐ_b_d_j_ˈuː_s_ə_n_z n_ˈɜː_v d_ɪ_z_ˈiː_z]\

Definitions of ABDUCENS NERVE DISEASE

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2010 - Medical Dictionary Database
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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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