7 BENZYLOXYRESORUFIN O DEALKYLASE
\sˈɛvən bˈɛnzɪlˌɒksɪɹˌɛsɔːɹˌuːfɪn ˈə͡ʊ dˈiːlkɪlˌe͡ɪs], \sˈɛvən bˈɛnzɪlˌɒksɪɹˌɛsɔːɹˌuːfɪn ˈəʊ dˈiːlkɪlˌeɪs], \s_ˈɛ_v_ə_n b_ˈɛ_n_z_ɪ_l_ˌɒ_k_s_ɪ_ɹ_ˌɛ_s_ɔː_ɹ_ˌuː_f_ɪ_n ˈəʊ d_ˈiː_l_k_ɪ_l_ˌeɪ_s]\
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A major cytochrome P-450 enzyme which is inducible by phenobarbital in both the liver and small intestine. It is active in the metabolism of compounds like pentoxyresorufin, testosterone, and androstenedione. CYP2B1 also mediates the activation of cyclophosphamide and ifosfamide to mutagens. EC 1.-.
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Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.