45S RNP
\fˈɔːtifˈa͡ɪv z ˌɑːɹˌɛnpˈiː], \fˈɔːtifˈaɪv z ˌɑːɹˌɛnpˈiː], \f_ˈɔː_t_i_f_ˈaɪ_v z ˌɑː_ɹ_ˌɛ_n_p_ˈiː]\
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Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.