12 HYDROXY 5,8,10,14 EICOSATETRAENOIC ACID
\twˈɛlv hˈa͡ɪdɹɒksi fˈa͡ɪv ˈe͡ɪt tˈɛn fˈɔːtiːn ˈa͡ɪkəsˌatɪtɹˌiːnə͡ʊɪk ˈasɪd], \twˈɛlv hˈaɪdɹɒksi fˈaɪv ˈeɪt tˈɛn fˈɔːtiːn ˈaɪkəsˌatɪtɹˌiːnəʊɪk ˈasɪd], \t_w_ˈɛ_l_v h_ˈaɪ_d_ɹ_ɒ_k_s_i f_ˈaɪ_v ˈeɪ_t t_ˈɛ_n f_ˈɔː_t_iː_n ˈaɪ_k_ə_s_ˌa_t_ɪ_t_ɹ_ˌiː_n_əʊ_ɪ_k ˈa_s_ɪ_d]\
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A lipoxygenase metabolite of ARACHIDONIC ACID. It is a highly selective ligand used to label mu-opioid receptors in both membranes and tissue sections. The 12-S-HETE analog has been reported to augment tumor cell metastatic potential through activation of protein kinase C. (J Pharmacol Exp Ther 1995; 274 (3):1545-51; J Natl Cancer Inst 1994; 86 (15):1145-51)
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
Nearby Words
- 115th
- 11614 r.p.
- 11th
- 12
- 12 hete
- 12 Hydroxy 5,8,10,14 eicosatetraenoic Acid
- 12 lipoxygenase
- 12 methoxyibogamine
- 12 myristoyl 13 acetylphorbol
- 12 o tetradecanoyl phorbol 13 acetate
- 12 r hete