11 DEHYDROPROSTAGLANDIN F2ALPHA
\ɪlˈɛvən dˌiːha͡ɪdɹˈɒpɹəstˌaɡlɐndˌɪn ˈɛf tˈuː ˈalfə], \ɪlˈɛvən dˌiːhaɪdɹˈɒpɹəstˌaɡlɐndˌɪn ˈɛf tˈuː ˈalfə], \ɪ_l_ˈɛ_v_ə_n d_ˌiː_h_aɪ_d_ɹ_ˈɒ_p_ɹ_ə_s_t_ˌa_ɡ_l_ɐ_n_d_ˌɪ_n ˈɛ_f t_ˈuː ˈa_l_f_ə]\
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The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects.
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Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.